Prepmaster 5100 Automated Coverslip Processor 

Prepmaster 5100 executing a dehydration step.

The Prepmaster 5100 automatically prepares cells seeded on coverslips for Transmission Electron Microscopy, Scanning Electron Microscopy and Light Microscopy.


Prepmaster 5100 Advantage

  • Effortlessly prepare cells seeded on coverslips in 24-well plates

  • Long protocols with > 5 heavy metal steps, such as OTO, can be run safely overnight

  • Example protocols included  

  • Your current manual workflow can be translated to this platform quickly and easily

  • Remote viewing and operation via RealVNC included

  • Easy to set up and easy to clean up


The Prepmaster 5100 ensures repeatability and reproducibility. It reliably accomplishes your dull, dangerous, repetitious, and error-prone tasks, increasing confidence in your results and freeing your time for more complex and interesting work.



  • Temperature controlled (5-95°C) sample dock

  • Prepares up to 24 coverslips per batch

  • Up to 72 unique reagents or rinses

  • Windows laptop computer control for fast, easy protocol creation and modification

  • Limitless number of protocols can be stored

  • Flat, low deck enables convenient in-hood installation or ventilated enclosure available

  • Expandable for future applications

  • Compact footprint: 63x57x66cm / 25x23x26in (w,d,h) 48kg (106lb) 100-240VAC 50/60Hz

Prepmaster 5100 Data Sheet

Robotic Specimen Prep Protocol Optimization for TEM using the xB0Tx™ Prepmaster™ 5100 Lab Robot: Astrocytes on Coverslips